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A7833 Sigma

Anti-ATF-1 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Properties

Related Categories AA - CA, AS-ATG, Alphabetical Index, Antibodies, Antibodies for Gene Regulation,
species reactivity   human
application(s)   microarray: suitable
  western blot (chemiluminescent): 1:500 using whole cell extract of human Jurkat acute T cell leukemia cells
clone   polyclonal
antibody form   affinity isolated antibody
form   buffered aqueous solution
mol wt   antigen mol wt 35-38 kDa
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... ATF1(466)
biological source   rabbit
conjugate   unconjugated

Description

Immunogen

synthetic peptide corresponding to human ATF-1, N-terminal sequence, amino acids 6-23, conjugated to KLH.

General description

ATF1 is a transcription factor that belongs to the bZIP (basic-region leucine zipper) family that may be modulated by cAMP. ATF1, along with EWS, have been implicated in malignant melanoma.
Rabbit Anti-ATF-1 antibody binds to human ATF1 by immunoblotting (35-38 kDa). An additional lower molecular weight band may be detected in some preparations. Staining of ATF1 by immunoblotting is inhibited by the immunizing peptide.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% BSA and 15 mM sodium azide.

Application

Rabbit Anti-ATF-1 antibody is suitable for western blot applications at 1:500.

Price and Availability


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