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A8054 Sigma

D(−)-2-Amino-5-phosphonopentanoic acid

NMDA receptor antagonist

Synonym: D(−)-AP-5, D(−)-APV, D-2-Amino-5-phosphonovaleric acid

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Excitatory Amino Acids, NMDA Antagonists, Neuroscience,
InChI Key   VOROEQBFPPIACJ-SCSAIBSYSA-N
optical purity   optical purity: ≥90% (HPLC, Marfey′s reagent)
Gene Information   mouse ... Grin2a(14811)
rat ... Grik1(29559), Grin2a(24409), Grin2b(24410), Grin2c(24411), Grin2d(24412)

Description

Biochem/physiol Actions

Anticonvulsant; potent and selective N-methyl-D-aspartate (NMDA) receptor antagonist; active enantiomer of 2-amino-5-phosphonopentanoic acid.

Packaging

1, 5, 10 mg in serum bottle

Price and Availability


All labs need water
Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
Protocols & Articles
Peer-Reviewed Papers
15

References

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