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A8054 Sigma

D(−)-2-Amino-5-phosphonopentanoic acid

NMDA receptor antagonist

DOWNLOAD MSDS (PDF)

Synonym: D(−)-AP-5, D(−)-APV, D-2-Amino-5-phosphonovaleric acid

D(−)-2-Amino-5-phosphonopentanoic acid NMDA receptor antagonist
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Properties

Related Categories A-AM, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Excitatory Amino Acids,
optical purity   optical purity: ≥90% (HPLC, Marfey′s reagent)
Gene Information   mouse ... Grin2a(14811)
rat ... Grik1(29559), Grin2a(24409), Grin2b(24410), Grin2c(24411), Grin2d(24412)

Description

Biochem/physiol Actions

Anticonvulsant; potent and selective N-methyl-D-aspartate (NMDA) receptor antagonist; active enantiomer of 2-amino-5-phosphonopentanoic acid.

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