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A8206 Sigma

Acacetin

Synonym: 5,7-Dihydroxy-4′-methoxyflavone

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Properties

Related Categories Bioflavonoids, Cell Biology, Nutrition Research, Phytochemicals by Chemical Classification
InChI Key   DANYIYRPLHHOCZ-UHFFFAOYSA-N
mp   260-265 °C(lit.)
storage temp.   2-8°C

Description

Biochem/physiol Actions

A flavonoid derivative possessing antioxidant properties. Induces cell cycle arrest and apoptosis in a time- and dose-dependent manner in several cancer cell lines in vitro.

Flavonoid with anti-peroxidative and anti-inflammatory properties. Used in traditional Chinese medicine. It has been recognized as an antiproliferative agent on cancer cell lines by inducing apoptosis and blocking cell cycle progression in the G1 phase.

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Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
DJ3002000
Protocols & Articles

Articles

Dietary Antioxidants

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.1 During the oxi...
Biofiles Volume 2 Article 2
Keywords: Adhesion, Anti-inflammatory agents, Applications, Cancer, Cardiovascular, Catalysis, Diabetes, Diseases, Gene expression, Metabolism, Neurodegenerative Diseases, Peroxidations, Phosphorylations, Prebiotics, Probiotics, Reductions, Transcription, Transduction, Vitamins

Peer-Reviewed Papers
15

References

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Product #

Description

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00017 Acacetin, ≥97.0% (HPLC)

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