|Related Categories||Cell Biology, Cell Signaling and Neuroscience, Natriuretic Peptides, Neuropeptides, Peptides and Proteins,|
|composition||Peptide content, ≥70%|
|Gene Information||rat ... Nppa(24602)|
Atrial natriuretic peptide (ANP) is synthesized in myoendocrine cells of the heart from which it is released into the circulation. It exerts natriuretic, diuretic, and vasodilatory effects through stimulation of guanylate cyclase-linked NPR-A receptors. It plays an important role in blood volume and blood pressure homeostasis.
The term ‘neuropeptidases’ refers to those enzymes that participate in the inactivation of synaptically released neuropeptides and therefore serve to turn off the generated peptide signal. In general...
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