|Related Categories||A - K, Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics A-F,|
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Bottomless glass bottle. Contents are inside inserted fused cone.
7-ADCA is produced from penicillin G made by Penicillium chrysogenum involving several polluting chemical steps followed by enzymatic deacylation using penicillin acylase 2.
Certificate of Analysis
Certificate of Origin
|Precautionary statements||P261-P280-P342 + P311|
|Personal Protective Equipment||dust mask type N95 (US), Eyeshields, Faceshields, Gloves|
|Hazard Codes (Europe)||Xn|
|Risk Statements (Europe)||42/43|
|Safety Statements (Europe)||36|
2. Mutational analysis of a key residue in the substrate specificity of a cephalosporin acylase. Linda G. Otten, Charles F. Sio, et al. ChemBioChem. 6, 820-825, (2004)
Anaerobic stabilization and conversion of transformed intermediates of antibiotic pharmaceutical effluent in a fluidized bed reactor. Tamijevendane S, Saravanane R, Rajesh R, et al. J. Environ. Sci. Eng. 53(3), 231-6, (2011)
Effect of loading rate and HRT on the removal of cephalosporin and their intermediates during the operation of a membrane bioreactor treating pharmaceutical wastewater. Saravanane R and Sundararaman S Environ. Technol. 30(10), 1016-22, (2009)
Penicillin acylase-catalyzed synthesis of beta-lactam antibiotics in highly condensed aqueous systems: beneficial impact of kinetic substrate supersaturation. Youshko MI, Moody HM, Bukhanov AL, et al. Biotechnol. Bioeng. 85(3), 323-9, (2004)
Kinetics of enzyme acylation and deacylation in the penicillin acylase-catalyzed synthesis of beta-lactam antibiotics. Alkema WB, de Vries E, Floris R, et al. Eur. J. Biochem. 270(18), 3675-83, (2003)
Continuous cultivations of a Penicillium chrysogenum strain expressing the expandase gene from Streptomyces clavuligerus: Growth yields and morphological characterization. Robin J, Lettier G, McIntyre M, et al. Biotechnol. Bioeng. 83(3), 361-8, (2003)
Enzyme reaction engineering: effect of methanol on the synthesis of antibiotics catalyzed by immobilized penicillin G acylase under isothermal and non-isothermal conditions. Travascio P, Zito E, Portaccio M, et al. Biotechnol. Prog. 18(5), 975-85, (2002)
Advantages of using non-isothermal bioreactors for the enzymatic synthesis of antibiotics: the penicillin G acylase as enzyme model. Travascio P, Zito E, De Maio A, et al. Biotechnol. Bioeng. 79(3), 334-46, (2002)
Continuous cultivations of a Penicillium chrysogenum strain expressing the expandase gene from Streptomyces clavuligerus: Kinetics of adipoyl-7-aminodeacetoxycephalosporanic acid and byproduct formations. Robin J, Bruheim P, Nielsen ML, et al. Biotechnol. Bioeng. 83(3), 353-60, (2003)
Quantitative characterization of the nucleophile reactivity in penicillin acylase-catalyzed acyl transfer reactions. Youshko MI, Chilov GG, Shcherbakova TA, et al. Biochim. Biophys. Acta 1599(1-2), 134-40, (2002)
Environmentally safe production of 7-aminodeacetoxycephalosporanic acid (7-ADCA) using recombinant strains of Acremonium chrysogenum. Velasco J, Luis Adrio J, Angel Moreno M, et al. Nat. Biotechnol. 18(8), 857-61, (2000)
Production of cephalosporin intermediates by feeding adipic acid to recombinant Penicillium chrysogenum strains expressing ring expansion activity. Crawford L, Stepan AM, McAda PC, et al. Biotechnology. (N.Y.) 13(1), 58-62, (1995)
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