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A8404 Sigma

Amitriptyline hydrochloride

≥98% (TLC), powder

Description

Features and Benefits

Shelf-life of the powder is at least three years.

Application

Amitriptyline hydrochloride is a tricyclic antidepressant drug. Amitriptyline hydrochloride inhibits the norepinephrine and serotonin transporters but has a high affinity for α1-adrenergic, serotonin and muscarinic acetylcholine receptors.

Biochem/physiol Actions

Tricyclic antidepressant; inhibits the norepinephrine and serotonin transporters with Kis of 100 nM and 14.7 nM, respectively; high in vitro affinity for α1-adrenoceptors, serotonin and muscarinic acetylcholine receptors.

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.




New TruPAGE™ Pre-cast Polyacrylamide Gels

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Amitriptyline hydrochloride

United States Pharmacopeia (USP) Reference Standard

Amitriptyline hydrochloride

pharmaceutical secondary standard; traceable to USP, PhEur and BP

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