Amitriptyline hydrochloride
≥98% (TLC), powder
DOWNLOAD MSDS (PDF)-
CAS Number 549-18-8
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Empirical Formula (Hill Notation) C20H23N · HCl
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Molecular Weight 313.86
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EC Number 208-964-6
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MDL number MFCD00012537
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PubChem Substance ID 24278073
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Popular Documents: FTNMR (PDF)
Properties
| Related Categories | A-AM, Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Biochemicals and Reagents, Biogenic Amine Transport Inhibitors, |
| assay | ≥98% (TLC) |
| form | powder |
| color | white to off-white |
| solubility | H2O: soluble |
| ethanol: soluble | |
| storage temp. | 2-8°C |
| Gene Information | human ... CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133) |
Description
Features and Benefits
Shelf-life of the powder is at least three years.
Application
Amitriptyline hydrochloride is a tricyclic antidepressant drug. Amitriptyline hydrochloride inhibits the norepinephrine and serotonin transporters but has a high affinity for α1-adrenergic, serotonin and muscarinic acetylcholine receptors.
Biochem/physiol Actions
Tricyclic antidepressant; inhibits the norepinephrine and serotonin transporters with Kis of 100 nM and 14.7 nM, respectively; high in vitro affinity for α1-adrenoceptors, serotonin and muscarinic acetylcholine receptors.
Price and Availability
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