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  • A8469 - Anti-Apaf1, N-Terminal antibody produced in rabbit

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A8469 Sigma

Anti-Apaf1, N-Terminal antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Properties

Related Categories AO-AQ, Alphabetical Index, Antibodies, Antibodies for Apoptosis, Antibodies for Cell Biology,
species reactivity   mouse, human
application(s)   microarray: suitable
  western blot: 0.5 μg/mL using a HeLa cell extract
clone   polyclonal
antibody form   affinity isolated antibody
form   buffered aqueous solution
mol wt   antigen mol wt 130 kDa
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... APAF1(317)
mouse ... Apaf1(11783)
biological source   rabbit
conjugate   unconjugated

Description

Immunogen

synthetic peptide corresponding to amino acids 12-28 of human Apaf1 (apoptosis protease-activating factor 1).

General description

APAF1 is a cytoplasmic apoptotic protease activating factor that funcitons in the formation of the apoptosome upon binding to cytochrome C to cleave caspase 9.

Apaf-1 is the mammalian equivalent of Ced-4. It forms a complex with cytochrome c and dATP that cleaves procaspase 9 to form activated caspase 9.

Rabbit Anti-Apaf1, N-Terminal antibody binds to human and mouse Apaf1.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Application

Rabbit Anti-Apaf1, N-Terminal antibody can be used for western blot (0.5μg/ml) and microarray applications.

Price and Availability


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