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A8699 Sigma

Activin Receptor IIA human

>95% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder

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Properties

Related Categories Activins, Activins and Inhibins, Cell Biology, Cell Signaling and Neuroscience, Cytokines and Growth Factors,
recombinant   expressed in baculovirus infected Sf21 cells
assay   >95% (SDS-PAGE)
form   lyophilized powder
impurities   endotoxin, tested
storage temp.   −20°C
Gene Information   human ... ACVR2A(92)

Description

Analysis Note

The biological activity is measured by its ability to inhibit hemoglobin expression induced by activin in K562 cells.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5 mg bovine serum albumin.

Biochem/physiol Actions

Activin isoforms are members of the TGF-β superfamily that bind to heteromeric complexes of a type I and a type II serine/threonine kinase receptor, both of which are essential for signal transduction. In addition to the activin isoforms, activin receptor II binds inhibin, BMP-2 and BMP-7. Human, murine and rat type II activin receptors demonstrate greater than 98% homology.

Price and Availability


All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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