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A8724 Sigma

ADP-ribosyltransferase C3 from Clostridium botulinum

Synonym: Botulinum neurotoxin C3, C3 Exoenzyme, C3 Exotoxin, C3 Transferase

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Description

Biochem/physiol Actions

Ribosylates rho in eukaryotes in the presence of NAD.

ADP-ribosyltransferase C3 from Clostridium botulinum ribosylates rho in eukaryotes in the presence of NAD. The ADP-ribosylating exoenzyme forms a single major 25 kDA (approx.) band with SDS electrophoresis. The enzyme labels 21-24 kDa proteins in tissues such as the human platelet membranes.

Application

ADP-ribosyltransferase C3 from Clostridium botulinum may be used to study cellular signaling and G protein expression .

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Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles

Related Content

Enzymes & Proteins

Application Index | Enzyme Index | Substrate Index | Inhibitor Index | Cofactor Index | Lectin Index
Keywords: Cell signaling, Diagnostic, Drug discovery, Molecular biology

Peer-Reviewed Papers
15

References

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