Anti-Amyloid Precursor Protein, N-Terminal antibody produced in rabbit
IgG fraction of antiserum, buffered aqueous solution
DOWNLOAD MSDS (PDF)Synonym: Anti-APP
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MDL number MFCD02095830
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Popular Documents: Datasheet (PDF)
Properties
| Related Categories | AM-AN, Alphabetical Index, Antibodies, Antibodies for Alzheimer′s Disease, Antibodies for Neurobiology, |
| species reactivity | rat, mouse, human |
| application(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:200 using formic acid-treated sections of human Alzheimer′s disease (AD) brain |
| microarray: suitable | |
| western blot: 1:1,000 using rat brain extract or supernatant of 293T cells secreting APP. | |
| clone | polyclonal |
| antibody form | IgG fraction of antiserum |
| form | buffered aqueous solution |
| mol wt | antigen mol wt 95-100 kDa |
| shipped in | dry ice |
| storage temp. | −20°C |
| Gene Information |
human ... APP(351) mouse ... App(11820) rat ... App(54226) |
Description
Immunogen
synthetic peptide corresponding to the N-terminal of human APP695 (amino acids 46-60) conjugated to KLH.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Specificity
The immunogen sequence is identical to the APP isoforms APP751 and APP770 and is highly conserved (single amino acid substitution) in rat and mouse APP695. The antibody recognizes APP695, APP751 and APP770.
Application
SH-SY5Y cell lysates were analyzed by western blot using rabbit anti-Amyloid Precursor Protein, C-Terminal as the primary antibody at a 1:500 dilution.
Price and Availability
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