EMAIL THIS PAGE TO A FRIEND
A9135 Sigma

Ethyl arachidonate

≥98.5% (GC), liquid

Synonym: 5,8,11,14-Eicosatetraenoic acid ethyl ester, Arachidonic acid ethyl ester

Purchase

Properties

Related Categories Biochemicals and Reagents, Esters, Ethyl Ester, Fatty Acids and conjugates, Fatty Acyls,
InChI Key   SNXPWYFWAZVIAU-GKFVBPDJSA-N
assay   ≥98.5% (GC)
form   liquid
storage temp.   −20°C

Description

Biochem/physiol Actions

Arachidonic acid (AA) is an unsaturated omega-6 fatty acid constituent of the phospholipids of cell membranes. Phospholipase A2 releases AA from the membrane phospholipids in response to inflammation. AA is subsequently metabolized to prostaglandins and thromboxanes by at least two cyclooxygenase (COX) isoforms, to leukotrienes and lipoxins by lipoxygenases, and to epoxyeicosatrienoic acids via p450-catalyzed metabolism. AA and its metabolites play important roles in a variety of biological processes, including signal transduction, contraction, chemotaxis, and cell proliferation, differentiation and apoptosis. AA has been demonstrated to bind to the α subunit of G protein and inhibit the activity of Ras GTPase-activating proteins (GAPs). Cellular uptake of AA is energy dependent and involves protein-facilitated transport across the plasma membrane.

Packaging

1 g in ampule

10, 100, 500 mg in ampule

Sealed ampule.

Price and Availability


The Future of Bioimaging
Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

related product

Product #

Description

Add to Cart

94791 SnapIT Ampule Opener, Regular, for 1-2ml, 5-10ml, 10-15ml ampoules
43917 SnapIT Ampule Opener, large, for 5-10ml, 10-15ml, 20-25ml ampoules

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?