A9393 Sigma

Ampicillin

anhydrous, 96.0-100.5% (anhydrous basis)

DOWNLOAD MSDS (PDF)

Synonym: D-(−)-α-Aminobenzylpenicillin

Description

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Biochem/physiol Actions

A β-lactam antibiotic with an amino group attached to the penicillin structure. Inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Bactericidal only to growing Escherichia coli. Mode of resistance: Cleavage of β-lactam ring of ampicillin by β-lactamase. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.

Application

Ampicillin is used to select bacteria cells with specific resistance during general microbiology studies. It is used to study antibiotic resistance and penetration limitations, the synergy between multiple antibiotics, certain bloodstream infections, and has been used to develop PCR assays to detect resistance genes in cerebrospinal fluid 1,2,3,4.

Price and Availability

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Ampicillin

meets USP testing specifications

Ready Made Solution, 100 mg/mL, 0.2 μm filtered

Ampicillin sodium salt

powder, BioReagent, suitable for cell culture

Ampicillin trihydrate

96.0-100.5% anhydrous basis (HPLC)

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