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A9454 Sigma

Activin Receptor IB human

>90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder

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Properties

Related Categories Activins, Activins and Inhibins, Cell Biology, Cell Signaling and Neuroscience, Cytokines and Growth Factors,
recombinant   expressed in NSO cells
assay   >90% (SDS-PAGE)
form   lyophilized powder
impurities   endotoxin, tested
storage temp.   −20°C
Gene Information   human ... ACVR1B(91)

Description

Biochem/physiol Actions

Activin receptor IB/Fc chimera does not bind directly to activin or inhibin but will associate with the type II receptor-activin complex and initiate signal transduction. Type I receptor-activins also bind and form signaling complexes with the BMP-2/7-bound BMPR-II. Activin isoforms are members of the TGF-β superfamily that bind to heteromeric complexes of type I and type II serine/threonine kinase receptor, both of which are essential for signal transduction. Human, murine and bovine type IB activin receptors demonstrate greater than 98% homology.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

Price and Availability

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
1

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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