Adenosine 3′,5′-cyclic monophosphate
≥98.5% (HPLC), powder
DOWNLOAD MSDS (PDF)Synonym: 3′,5′-Cyclic AMP, Adenosine 3′,5′-cyclophosphate, cAMP
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CAS Number 60-92-4
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Empirical Formula (Hill Notation) C10H12N5O6P
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Molecular Weight 329.21
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Beilstein Registry Number 52645
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EC Number 200-492-9
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MDL number MFCD00005845
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PubChem Substance ID 24278245
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Popular Documents: Specification Sheet (PDF) | FTNMR (PDF)
Properties
| Related Categories | A-AM, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cyclic Nucleotide Metabolism, |
| assay | ≥98.5% (HPLC) |
| form | powder |
| color | white |
| mp | 260 °C (dec.)(lit.) |
| solubility | H2O: soluble10 mg/mL, clear, colorless (pH of aqueous solution is approx. 3.0. The sodium salt (A6885) is about 20× more soluble.) |
| storage temp. | −20°C |
| Gene Information | human ... OPRK1(4986) |
Description
Packaging
1, 5, 25 g in poly bottle
Biochem/physiol Actions
Naturally-occurring activator of cyclic-AMP-dependent protein kinase (PKA). cAMP is an important second messenger that is linked in many systems to neurotransmitter- or hormone-induced receptor stimulation. The cAMP/PKA signaling pathway has been shown to inhibit cell proliferation, induce differentiation and lead to apoptosis.
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