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A9511 Sigma

Albumin from human serum

lyophilized powder, ≥97% (agarose gel electrophoresis)

Synonym: HSA



Related Categories Albumin, Biochemicals and Reagents, Human Serum Albumins, Proteins and Amino Acids for Protein Stabilization, Proteins and Derivatives,
assay   ≥97% (agarose gel electrophoresis)
form   lyophilized powder
mol wt   monomer calculated mol wt 66478 Da
impurities   HIV I and HIVII, HCV and HBsAg, tested negative
solubility   H2O: soluble 50 mg/mL
storage temp.   2-8°C
Gene Information   human ... ALB(213)


Frequently Asked Questions

Frequently Asked Questions are available for this Product.

Other Notes

View more information on human serum albumin.


1, 5, 10, 25 g in poly bottle

100, 500 mg in poly bottle

Preparation Note

Prepared using method IV of Cohn, E.J., et al., J. Am. Chem. Soc., 69, 1753 (1947).


Albumin-bound fluorescence was used in serum of patients with chronic renal failure.

Biochem/physiol Actions

Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones, and is vital in regulating the colloidal osmotic pressures of blood. Albumin is also seen to bind to exogenous substances, particularly drugs (e.g., ibuprofen, warfarin), and strongly influence their pharmacokinetics. Oxidative stress leading to changes in the redox state of albumin has widely varied effects on its physiological function.

General description

Albumin is the most copious protein in blood plasma. Liver produces human albumin.

Price and Availability

Safety & Documentation

Safety Information

Personal Protective Equipment 
NONH for all modes of transport
WGK Germany 

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis. These documents are located on the product detail page under Useful Links & Tools. Click on the following link to search for a Certificate of Analysis. Please click the following link to see the details on our Product Dating Information.
How do I get lot-specific information or a Certificate of Analysis?
A Certificate of Analysis is available by lot number and can be obtained through our Advanced Search Option: http://www.sigmaaldrich.com/catalog/AdvancedSearchPage.do
How do I find price and availability?
There are several ways to find pricing and availability for our products.  Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers. 
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS. To access the shipping information for this material, use the link on the product detail page for the product, or search here. 
Can Product A9511, Human serum albumin (HSA), be used for cell culture applications?
Although A9511 is not sterile or endotoxin tested, it can probably still be used in cell culture. Filtering a solution of HSA through a 0.45 micron filter, then a 0.2 micron filter would provide a solution that is sterile, and likely suitable for cells. A5843 is an HSA product that has been endotoxin tested.
What are the impurities for Product A9511, Human serum albumin (HSA)?
The impurities present are alpha-globulin and beta-globulin.
My question is not addressed here, how can I contact Technical Service for assistance?
Use the option to the right to "Ask a Question" by email of a Technical Service Scientist.
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Protocols & Articles

Related Content

Albumin in Cell Culture

Importance and uses of albumin in serum-free eucaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell cultures
Keywords: Cell culture, Culture media, Degradations, Hormones, Ligands, Oxidations, PAGE, Purification, Redox Reactions

Peer-Reviewed Papers


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