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A9736 Sigma

A-438079 hydrochloride hydrate

≥98% (HPLC)

Synonym: 3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methyl pyridine hydrochloride hydrate

  • Empirical Formula (Hill Notation) C13H9Cl2N5·HCl · xH2O

  • Molecular Weight 342.61 (anhydrous basis)

  •  MDL number MFCD17215929

  •  PubChem Substance ID 329771058

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Properties

Related Categories A-AM, Abbott, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules,
InChI Key   ZHFJJBAKSROKNO-UHFFFAOYSA-N
assay   ≥98% (HPLC)
form   powder
storage condition   desiccated
color   white to beige
solubility   DMSO: soluble20 mg/mL, clear
originator   Abbott
storage temp.   2-8°C

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

A-438079 hydrochloride hydrate is a selective P2X7 purinoceptor antagonist in both human and rat with minimal activity at 75 different G-protein-coupled receptors, enzymes, transporters, and ion channels tested.

Features and Benefits

This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles

Articles

P2 Receptors: P2X Ion Channel Family

Once known as P2 purinoreceptors, surface receptors for extracellular nucleotides are now called P2 receptors. This subtle change in nomenclature reflects the more varied nature of nucleotidic ligand...
Keywords: Apoptosis, Atomic absorption spectroscopy, Gene expression, Inflammation, Ligands, Magnetic resonance spectroscopy, Polymorphisms, Transcription, Transduction

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