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A9808 Sigma

Pituitary adenylate cyclase activating polypeptide-27 ovine

≥97% (HPLC), solid

Synonym: PACAP-27

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Properties

Related Categories Adenylate Cyclase Activators, Adenylyl Cyclase Activators, Cell Biology, Cell Signaling and Neuroscience, Cyclic Nucleotide Metabolism,
InChI Key   RZGBUJXSKLDAFE-UHFFFAOYSA-N
assay   ≥97% (HPLC)
form   solid
composition   Peptide content, ≥65%
color   white
storage temp.   −20°C
Gene Information   human ... ADCY1(107)
mouse ... ADCY1(432530)
rat ... ADCY1(305509)
sheep ... PACAP(443337)

Description

Amino Acid Sequence

His-Ser-Asp-Gly-Ile-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-NH2

Biochem/physiol Actions

Neuropeptide that stimulates both adenylate cyclase in cultured pituitary cells and insulin release from pancreatic islet β-cells. Increases cAMP levels; increases tyrosine hydroxylase expression in chromaffin cells.

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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