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A9809 Sigma

Amsacrine hydrochloride

≥98% (TLC), powder

Synonym: 4-(9-Acridinylamino)-N-(methanesulfonyl)-m-anisidine hydrochloride, m-AMSA

  • CAS Number 54301-15-4

  • Empirical Formula (Hill Notation) C21H19N3O3S · HCl

  • Molecular Weight 429.92

  •  MDL number MFCD07799963

  •  PubChem Substance ID 24278248

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Properties

Related Categories A-AM, Apoptosis and Cell Cycle, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents,
InChI Key   WDISRLXRMMTXEV-UHFFFAOYSA-N
assay   ≥98% (TLC)
form   powder
color   red to brown
mp   197-199 °C(lit.)
solubility   DMSO: soluble10 mg/mL (with heat and sonication)
  30% ethanol: soluble4 mg/mL
Gene Information   human ... TOP2A(7153), TOP2B(7155)

Description

Biochem/physiol Actions

Amsacrine hydrochloride is a DNA topoisomerase II inhibitor.

Packaging

10, 50 mg in poly bottle

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Price and Availability


DISCOVER Bioactive Small Molecules

Flow Cytometry Instruments

All labs need water
Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
RTECS 
PB1081000

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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