Synonym: Coumarin 120
|Related Categories||Activity, Biochemicals and Reagents, Enzyme Substrates, Enzymes, Inhibitors, and Substrates, Fluorogenic,|
|description||chromophore for enzyme substrates|
|fluorescence||λex 365 nm; λem 440 nm in ethanol(lit.)|
Used as matrix for analysis of monosulfated disaccharides and as a co-matrix with 6-aza-2-thiothymidine for sulfated neutral and sialylated tri-and tetrasaccharides.
Reagent for preparing new fluorogenic AMC-based substrates for cystine aminopeptidase (and other hydrolases); used as reference compound in the enzyme assay.
1, 5 g in poly bottle
250, 500 mg in poly bottle
Soluble in DMSO (10 mg/mL), DMF, and acetone (10 mg/mL).
Certificate of Analysis
Certificate of Origin
|Precautionary statements||P261-P305 + P351 + P338|
|Personal Protective Equipment||dust mask type N95 (US), Eyeshields, Gloves|
|Hazard Codes (Europe)||Xi|
|Risk Statements (Europe)||36/37/38|
|Safety Statements (Europe)||26-36|
In 1998 R.F. Furchgott, L.J. Ignarro, and F. Murad received the Nobel Prize in Physiology and Medicine for their discoveries concerning nitric oxide as a signaling molecule in the cardiovascular syst...
BioFiles 2011, 6.3, 23.
Keywords: Biochemistry, Biological processes, Cancer, Cardiovascular, Central Nervous System, Diseases, Extinction coefficient, Indicators, Inflammation, Microscopy, Neurotransmission, Sol-gel
1. OBJECTIVE To standardize a procedure for determining the enzymatic activity of Cathepsin B.
Keywords: Enzyme activity, Enzymology
Khammungkhune, S. and Sigler, G. Synthesis, 614, (1980)
Aldrich MSDS 1, 92:B / Corp MSDS 1 (1), 190:D / FT-IR 1 (2), 328:D / FT-IR 2 (2), 2914:B / FT-NMR 1 (2), 1318:C / NMR-Reference 2 (2), 313:B / RegBook 1 (2), 1945:O / Sigma FT-IR 1 (2), 98:C / Structure Index 1, 313:A:5
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