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A9968 Sigma

N-Acetyl-Ile-Glu-Thr-Asp-p-nitroanilide

≥95%

Synonym: Ac-IETD-pNA

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Description

Amino Acid Sequence

NAc-Ile-Glu-Thr-Asp-pNA

Application

Chromogenic substrate for caspase 8 and granzyme B.

Biochem/physiol Actions

IETD is the sequence of amino acid residues 172-175 of procaspase 3, which is cleaved during apoptosis to produce the p12 subunit and a p20 peptide that is further cleaved to form the p17 subunit of mature caspase 3.

Packaging

5 mg in glass bottle

Price and Availability


Flow Cytometry Instruments

All labs need water

Amicon Ultra Centrifugal Filters
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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