B0300 Sigma

Betaine solution

5 M, PCR Reagent


Related Categories Biochemicals, Molecular Biology, Molecular Biology Reagents, PCR Enhancers, PCR Reaction Components,
grade   PCR Reagent
packaging   vial of 1.5 mL
concentration   5 M
foreign activity   DNase, RNase, none detected
storage temp.   2-8°C



The addition of betaine at a final concentration of 0.8-1.6M improves the amplification of DNA by reducing the formation of secondary structure in GC-rich regions. The addition of betaine has been reported to enhance the specificity of the polymerase chain reaction by eliminating the base pair composition dependence of DNA melting.1


1.5mL per vial

Price and Availability

PCR Selection Guide

PCR Selection GuideNeed help choosing between Taq® and ReadyMix™ products?

Use our interactive PCR selection guide to help you choose the right product for your research needs.

Customers Also Viewed


≥98% (perchloric acid titration)


BioUltra, ≥99.0% (NT)

Betaine hydrochloride

BioUltra, ≥99%

Betaine monohydrate

≥99.0% (NT)

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?