B102 Sigma

Bupropion hydrochloride

≥98% (HPLC), solid

DOWNLOAD MSDS (PDF)

Synonym: (±)-1-(3-Chlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone hydrochloride

  • CAS Number 31677-93-7

  • Empirical Formula (Hill Notation) C13H18ClNO · HCl

  • Molecular Weight 276.20

  •  EC Number 250-759-9

  •  MDL number MFCD00055209

  •  PubChem Substance ID 24277884

Properties

Related Categories Approved Therapeutics/Drug Candidates, B, Bioactive Small Molecules, Biochemicals and Reagents, Biogenic Amine Transport Inhibitors,
assay   ≥98% (HPLC)
form   solid
color   white
solubility   ethanol: soluble193 mg/mL (solutions may be stored for several days at 4 °C.)
  H2O: soluble312 mg/mL (solutions may be stored for several days at 4 °C.)
  1 M HCl: soluble333 mg/mL (solutions may be stored for several days at 4 °C.)
Gene Information   human ... DRD1(1812), DRD2(1813), DRD3(1814), DRD4(1815), DRD5(1816)

Description

Biochem/physiol Actions

Inhibits the dopamine and norepinephrine transporters with Kis of 2.8 μM and 1.4 μM, respectively. Does not inhibit the serotonin transporter (Ki = 45 μM). Antidepressant.

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