Synonym:
(±)
CAS Number 31677-93-7
Empirical Formula (Hill Notation) C13H18ClNO · HCl
Molecular Weight 276.20
EC Number 250-759-9
MDL number MFCD00055209
PubChem Substance ID 24277884
| Related Categories | Approved Therapeutics/Drug Candidates, B, Bioactive Small Molecules, Biochemicals and Reagents, Biogenic Amine Transport Inhibitors, |
| assay | ≥98% (HPLC) |
| form | solid |
| color | white |
| solubility | ethanol: soluble193 mg/mL (solutions may be stored for several days at 4 °C.) |
| H2O: soluble312 mg/mL (solutions may be stored for several days at 4 °C.) | |
| 1 M HCl: soluble333 mg/mL (solutions may be stored for several days at 4 °C.) | |
| Gene Information | human ... DRD1(1812), DRD2(1813), DRD3(1814), DRD4(1815), DRD5(1816) |
Inhibits the dopamine and norepinephrine transporters with Kis of 2.8 μM and 1.4 μM, respectively. Does not inhibit the serotonin transporter (Ki = 45 μM). Antidepressant.
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