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B1174 Sigma

BiP from calf liver

~96% (SDS-PAGE)

Synonym: GRP78, Immunoglobulin-heavy-chain binding protein

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, ER Resident Proteins, Endoplasmic Reticulum Stress
assay   ~96% (SDS-PAGE)
mol wt   mol wt ~78 kDa
solubility   H2O: soluble0.1 mg/mL, clear to hazy
storage temp.   −20°C

Description

Biochem/physiol Actions

BiP is a member of the hsp70 family of chaperone proteins and is the major chaperone in endoplasmic reticulum (ER) lumen. It is involved in protein folding and translocation through the ER membranes. BiP displays a low basal level of ATPase activity that is stimulated by various peptides. It is activated by Ca2+ and also serves as a Ca2+ storage protein in the ER lumen.

Other Notes

Lyophilized powder containing 20 mM HEPES, pH 7.5, 25 mM KCl, 5 mM MgCl2, and 100 mg/ml trehalose.

Price and Availability

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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