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B1183 Sigma

1-Benzoyl-5-methoxy-2-methylindole-3-acetic acid

solid

  • Empirical Formula (Hill Notation) C19H17NO4

  • Molecular Weight 323.34

  •  MDL number MFCD03452837

  •  PubChem Substance ID 24278255

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Properties

Related Categories Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Drug Efflux Pumps, Drug Transport Compounds,
InChI Key   AWPBTRHQEYHZJD-UHFFFAOYSA-N
assay   ≥97% (HPLC)
form   solid
color   white
solubility   H2O: slightly soluble <0.17 mg/mL
  DMSO: soluble38 mg/mL
storage temp.   2-8°C
Gene Information   human ... ABCC1(4363)

Description

Biochem/physiol Actions

Putative inhibitor of multidrug resistance-associated protein 1 (MRP1).

Other Notes

N-benzoyl analog of indomethacin.

Price and Availability

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles

Articles

Drug Transport

Protein-based drug transporters are found in most tissues including liver, kidney, intestine, and brain. Because of their complexity and genetic heterogeneity, these proteins are often produced as re...
Robert Gates
Biofiles Volume 6 Article 1
Keywords: Absorption, Anti-inflammatory agents, Antibiotics, Antimicrobials, Apoptosis, Cancer, Catalog, Cytotoxins, Detoxification, Enzyme-linked immunosorbent assay, Gene expression, Genetic, High performance liquid chromatography, Immunohistochemistry, Mass spectrometry, Metabolites, Methods, Phosphorylations, Separation, The Reporter, Transfection, Type, Western blot

Peer-Reviewed Papers
15

References

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