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B1682 Sigma

BAD from mouse

≥70% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous glycerol solution

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Properties

Related Categories Apoptosis and Cell Cycle, Bcl-2 Family Proteins, Bcl-2 Family Proteins and Antibodies, Biochemicals and Reagents, Cell Biology,
recombinant   expressed in E. coli
description   full-length murine Bad with an N-terminal histidine-tag.
assay   ≥70% (SDS-PAGE)
form   buffered aqueous glycerol solution
mol wt   mol wt 31 kDa
storage temp.   −20°C
Gene Information   mouse ... Bad(12015)

Description

Physical form

Supplied as a solution in phosphate buffered saline containing 250 mM imidizole and 50% glycerol.

Biochem/physiol Actions

Bad, a pro-apoptotic factor, is a member of the Bcl-2 family. Cytokine-induced phosphorylation of Bad results in it being sequested in the cytosol. In the absence of cytokines such as interleukin 3 (IL-3), Bad dephosphorylation occurs, causing the release of cytochrome c from the mitochondria.

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Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
2
Protocols & Articles
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