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B169 Sigma

BRL 37344 sodium salt hydrate

solid

Synonym: (±)-(R*,R*)-[4-[2-[[2-(3-Chlorophenyl)-2-hydroxyethyl]amino]propyl]phenoxy]acetic acid sodium hydrate, BRL 37344A

  • CAS Number 127299-93-8 (anhydrous)

  • Empirical Formula (Hill Notation) C19H21ClNNaO4 · xH2O

  • Molecular Weight 385.82 (anhydrous basis)

  •  PubChem Substance ID 24277764

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Properties

Related Categories Adrenergics, Agonists, B, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules,
InChI Key   YTPAKDODIXRQTF-BNTHFPBMSA-M
assay   ≥98% (HPLC)
form   solid
color   white
solubility   DMSO: soluble18 mg/mL, clear (warmed)
Gene Information   human ... ADRB3(155)

Description

Caution

Hygroscopic; store desiccated.

Biochem/physiol Actions

BRL 37344 is a selective β3-adrenoceptor agonist. Studies support the hypothesis that there are peripheral β3 adrenergic receptors that can reduce food intake and that central β2 or β3 adrenergic receptors mediate the peripheral effects of the β3 agonist.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Price and Availability


All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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