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B1883 Sigma

Benzidine

ISOPAC®, ≥98.0% (N)

Synonym: 4,4′-Diaminobiphenyl

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Properties

Related Categories B, Cell Biology, Hematology and Histology, Stains & Dyes, A to Z, Stains and Dyes More...
InChI Key   HFACYLZERDEVSX-UHFFFAOYSA-N
assay   ≥98.0% (N)
Gene Information   human ... UGT1A4(54657)

Description

Biochem/physiol Actions

Tumor initiator in mammalian liver and urinary bladder.

Caution

OSHA′s Safety and Health Standard 29 CFR 1910 does not apply to a solution or mixture containing less than 0.1%. Injecting a compatible solvent permits preparation of any desired strength solution without exposure to benzidine.

Packaging

100 mg in serum bottle

Packaged in a 100 mL serum bottle with butyl rubber stopper and aluminum tear seal.

Reconstitution

Dissolving the contents in 100 mL of solvent yields a 0.1% solution.

Application

Benzidine (4,4′-Diaminobiphenyl) is an environmental genotoxin that posses increased risks of cancer to exposed people. Benzidine may be used as a reference material in procedures that analyze for benzidine. Benzidine can be used in studies on its mechanisms of genotoxicity.

Legal Information

Isopac is a registered trademark of Sigma-Aldrich Co. LLC

Price and Availability


All labs need water
Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
RIDADR 
UN 1885 6.1 / PGII
WGK Germany 
3
RTECS 
DC9625000

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Carcinogenesis and Epigenetics

Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete. The expansion of the carcinogenesi...
Vicki Caligur
BioFiles 2008, 3.5, 18.
Keywords: Acetylations, Adhesion, Alkylations, Apoptosis, Biofiles, Cancer, Carcinogens, Cell division, Cell proliferation, Cell signaling, DNA microarrays, Drug discovery, Environmental, Epigenetics, Events, Gene expression, Genetic, Hormones, Metabolism, Methylations, Microarray Analysis, Mutagens, PAGE, Recombination, Reductions, Sequences, Transcription, Type, transformation

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Peer-Reviewed Papers
15

References

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B3503 Benzidine, ≥98.0% (N)

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