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B2515 Sigma

L-Buthionine-sulfoximine

≥97% (TLC)

Synonym: L-BSO

Description

Biochem/physiol Actions

Blocks cellular resistance to chemotherapy by inhibiting γ-glutamylcysteine synthetase, a key enzyme in glutathione biosynthesis.2 Used to induce experimental glutathione deficiency, to investigate roles of glutathione in cellular processes.1

Packaging

1, 5 g in poly bottle

500 mg in poly bottle

Application

Used to induce experimental glutathione deficiency, to investigate roles of glutathione in cellular processes.1

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®,1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.



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