|Related Categories||B, Bioactive Small Molecules, Biochemicals and Reagents, Cancer Research, Cell Biology,|
|Gene Information||human ... GCLC(2729), GCLM(2730)|
Blocks cellular resistance to chemotherapy by inhibiting γ-glutamylcysteine synthetase, a key enzyme in glutathione biosynthesis.2 Used to induce experimental glutathione deficiency, to investigate roles of glutathione in cellular processes.1
1, 5 g in poly bottle
500 mg in poly bottle
Used to induce experimental glutathione deficiency, to investigate roles of glutathione in cellular processes.1
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HSV infection induces production of ROS, which potentiate signaling from pattern recognition receptors: role for S-glutathionylation of TRAF3 and 6. Gonzalez-Dosal R PLoS Pathog. 7(9), e1002250, (2011)
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