Synonym: Natural Yellow 18
|Related Categories||Alkaloid, Anti-Proliferative Agents, Antitumor Agents, B, Bioactive Small Molecules,|
Fluorescent stain for heparin in mast cells
An alkaloid with weak antibiotic properties. Substrate for MDR efflux pumps. Antimicrobial activities of berberine is potentiated by the MDR inhibitor 5´-methoxyhydnocarpin (5´-MHC). Berberine upregulates the expression of Pgp in hepatoma cells. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs.
5, 10, 25 g in glass bottle
Protein-based drug transporters are found in most tissues including liver, kidney, intestine, and brain. Because of their complexity and genetic heterogeneity, these proteins are often produced as re...
Biofiles Volume 6 Article 1
Keywords: Absorption, Anti-inflammatory agents, Antibiotics, Antimicrobials, Apoptosis, Cancer, Cytotoxins, Detoxification, Enzyme-linked immunosorbent assay, Gene expression, Genetic, High performance liquid chromatography, Immunohistochemistry, Mass spectrometry, Metabolites, Phosphorylations, Separation, Transfection, Western blot
Berberine analogues as a novel class of the low-density-lipoprotein receptor up-regulators: synthesis, structure-activity relationships, and cholesterol-lowering efficacy. Ying-Hong Li et al J. Med. Chem. 52, 492-501, (2009)
Synthesis and evaluation of 9-O-substituted berberine derivatives containing aza-aromatic terminal group as highly selective telomeric G-quadruplex stabilizing ligands. Yan Ma et al Bioorg. Med. Chem. Lett. 19, 3414-7, (2009)
Synthesis and biological evaluation of berberine analogues as novel up-regulators for both low-density-lipoprotein receptor and insulin receptor. Yan-Xiang Wang et al Bioorg. Med. Chem. Lett. 19, 6004-8, (2009)
Probing of the cis-5-phenyl proline scaffold as a platform for the synthesis of mechanism-based inhibitors of the Staphylococcus aureus sortase SrtA isoform. Konstantin V Kudryavtsev et al Bioorg. Med. Chem. 17, 2886-93, (2009)
Inhibitors of prolyl oligopeptidases for the therapy of human diseases: defining diseases and inhibitors. Lawandi J, Gerber-Lemaire S, Juillerat-Jeanneret L, Moitessier N. J. Med. Chem. 53, 3423-3438, (2010)
Berberine derivatives, with substituted amino groups linked at the 9-position, as inhibitors of acetylcholinesterase/butyrylcholinesterase. Ling Huang et al Bioorg. Med. Chem. Lett. 20, 6649-52, (2010)
Synthesis and biological evaluation of a new series of berberine derivatives as dual inhibitors of acetylcholinesterase and butyrylcholinesterase. Ling Huang et al Bioorg. Med. Chem. 18, 4475-84, (2010)
Berberine-INF55 (5-nitro-2-phenylindole) hybrid antimicrobials: effects of varying the relative orientation of the berberine and INF55 components. Danuta Tomkiewicz et al Antimicrob. Agents Chemother. 54, 3219-24, (2010)
Synthesis, biological evaluation and molecular modeling of novel triazole-containing berberine derivatives as acetylcholinesterase and ?-amyloid aggregation inhibitors. Anding Shi et al Bioorg. Med. Chem. 19, 2298-305, (2011)
Quinolino-benzo-[5, 6]-dihydroisoquindolium compounds derived from berberine: a new class of highly selective ligands for G-quadruplex DNA in c-myc oncogene. Yan Ma et al Eur. J. Med. Chem. 46, 1906-13, (2011)
Discovery of estrogen receptor ? modulators from natural compounds in Si-Wu-Tang series decoctions using estrogen-responsive MCF-7 breast cancer cells. Li Liu et al Bioorg. Med. Chem. Lett. 22, 154-63, (2012)
The fluorescent staining of heparin in mast cells using berberine sulfate: compatibility with paraformaldehyde or o-phthalaldehyde induced fluorescence and metachromasia. Dimlich, R.V.W., et al. Stain Technol. 55, 217, (1980)
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