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B3259 Sigma

Bradykinin acetate salt

powder, ≥98% (HPLC)

  • CAS Number 6846-03-3

  • Empirical Formula (Hill Notation) C50H73N15O11 · xC2H4O2

  • Molecular Weight 1060.21 (free base basis)

  •  EC Number 227-781-2

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Properties

Related Categories Bradykinins, Cell Biology, Cell Signaling and Neuroscience, Neuropeptides, Peptides and Proteins,
assay   ≥98% (HPLC)
form   powder
storage condition   desiccated
color   white
solubility   0.1 M acetic acid: soluble25 mg/mL, clear, colorless
storage temp.   −20°C
Gene Information   human ... KNG1 (includes EG:3827)(3827)

Description

Amino Acid Sequence

Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg

Biochem/physiol Actions

Bradykinin is a pro-inflammatory peptide that acts through G-protein-coupled receptors. It activates sphingolipid metabolism. Fibroblasts treated with bradykinin produce a rapid and important increase in ceramide which is followed by a transient rise in sphingosine content. The peptide also increases ceramide cellular content by rapidly mobilizing neutral glycolipids. Bradykinin plays an important role in the regulation of fluid and electrolyte balance, smooth muscle contraction, vasodilation and capillary permeability. The bradykinin potentiators, which possess no bradykinin activity themselves, enhance the activity of bradykinin.

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Amicon Ultra Centrifugal Filters
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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06693 Timestrip Plus -20 °C

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