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B3805 Sigma

Anti-Bone Morphogenetic Protein 5 antibody produced in goat

affinity isolated antibody, lyophilized powder

Synonym: Anti-BMP-5

Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Kinase/Phosphatase Biology, Antibodies to Cytokines and Growth Factors,
species reactivity   human
application(s)   immunohistochemistry (frozen sections): 5-15 μg/mL
  neutralization: suitable
  western blot: 0.1 μg/mL
clone   polyclonal
antibody form   affinity isolated antibody
form   lyophilized powder
storage temp.   −20°C
Gene Information   human ... BMP5(653)
biological source   goat
conjugate   unconjugated
Featured Industry   Research Pathology

Description

Immunogen

recombinant human BMP-5, expressed in NSO cells.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

Biochem/physiol Actions

Bone morphogenetic proteins (BMPs) are the members of the TGF-β superfamily and are identified as the critical factors for formation of bone and cartilage. Apart from this BMPs have immune regulatory functions. The cellular effects of BMPs are mediated by a heteromeric complex composed of type I and type II receptors. BMP5 is required for the development and fine tuning of the skeletal morphology.

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