|Related Categories||Apoptosis and Cell Cycle, BRDU Cell Proliferation Assay Reagents, Biochemicals and Reagents, Cancer Research, Cell Biology,|
|mp||191-194 °C (dec.)(lit.)|
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Thymidine analog used as a mutagen in genetic research. Selectively incorporated into cellular DNA during S-phase.
1, 5, 100 g in glass bottle
100, 250, 500 mg in glass bottle
5-Bromo-2′-deoxyuridine (5-BrdU) is a thymidine analogue which is incorporated into DNA. 5-BrdU is routinely and extensively used to measure DNA synthesis and to label dividing cells. Consequently 5-BrdU is used to study cell signaling and other processes that induce cell proliferation.
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thymidylate synthase inhibitor
~1.5 mg/mL, clone BU-33, purified immunoglobulin, buffered aqueous solution
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Certificate of Origin
|Precautionary statements||P201-P281-P308 + P313|
|Personal Protective Equipment||Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter|
|Hazard Codes (Europe)||T|
|Risk Statements (Europe)||46-61|
|Safety Statements (Europe)||53-45|
We studied autocrine transforming growth factor (TGF)beta signaling in kidney epithelium. Cultured proximal tubule cells showed regulated signaling that was high during log-phase growth, low during c...
H Geng, R Lan, G Wang, AR Siddiqi, MC Naski, AI Brooks, JL Barnes, P Saikumar, JM Weinberg, MA Venkatachalam
The American Journal of Pathology 2009-04-01
Keywords: Growth factors
Impact of environmental enrichment on neurogenesis in the dentate gyrus during the early postnatal period. Rizzi S, Bianchi P, Guidi S, et al. Brain Res., (2011)
A comparative analysis of intraperitoneal versus intracerebroventricular administration of bromodeoxyuridine for the study of cell proliferation in the adult rat brain. Cifuentes M, Pérez-Martín M, et al. J. Neurosci. Methods 201(2), 307-14, (2011)
Multiple helminth infection of the skin causes lymphocyte hypo-responsiveness mediated by Th2 conditioning of dermal myeloid cells. Cook PC, Aynsley SA, Turner JD, et al. PLoS Pathog. 7(3), e1001323, (2011)
Mutant presenilin 1 expression in excitatory neurons impairs enrichment-mediated phenotypes of adult hippocampal progenitor cells. Veeraraghavalu K and Sisodia SS Proc. Natl. Acad. Sci. U. S. A. 110(22), 9148-53, (2013)
Lacosamide treatment following status epilepticus attenuates neuronal cell loss and alterations in hippocampal neurogenesis in a rat electrical status epilepticus model. Licko T, Seeger N, Zellinger C, et al. Epilepsia 54(7), 1176-85, (2013)
MicroRNA-92b regulates the development of intermediate cortical progenitors in embryonic mouse brain. Nowakowski TJ, Fotaki V, Pollock A, et al. Proc. Natl. Acad. Sci. U. S. A. 110(17), 7056-61, (2013)
Zif268/egr1 gene controls the selection, maturation and functional integration of adult hippocampal newborn neurons by learning. Veyrac A, Gros A, Bruel-Jungerman E, et al. Proc. Natl. Acad. Sci. U. S. A. 110(17), 7062-7, (2013)
Reduced adult hippocampal neurogenesis and working memory deficits in the Dgcr8-deficient mouse model of 22q11.2 deletion-associated schizophrenia can be rescued by IGF2. Ouchi Y, Banno Y, Shimizu Y, et al. J. Neurosci. 33(22), 9408-19, (2013)
MPP3 is required for maintenance of the apical junctional complex, neuronal migration, and stratification in the developing cortex. Dudok JJ, Sanz AS, Lundvig DM, et al. J. Neurosci. 33(19), 8518-27, (2013)
Physical exercise prevents stress-induced activation of granule neurons and enhances local inhibitory mechanisms in the dentate gyrus. Schoenfeld TJ, Rada P, Pieruzzini PR, et al. J. Neurosci. 33(18), 7770-7, (2013)
Fgf10-expressing tanycytes add new neurons to the appetite/energy-balance regulating centers of the postnatal and adult hypothalamus. Haan N, Goodman T, Najdi-Samiei A, et al. J. Neurosci. 33(14), 6170-80, (2013)
New striatal neurons in a mouse model of progressive striatal degeneration are generated in both the subventricular zone and the striatal parenchyma. Luzzati F, De Marchis S, Parlato R, et al. PLoS ONE 6(9), e25088, (2011)
Substituted benzyl-pyrimidines targeting thymidine monophosphate kinase of Mycobacterium tuberculosis: synthesis and in vitro anti-mycobacterial activity. Cécile Gasse et al Bioorg. Med. Chem. 16, 6075-85, (2008)
Boccadoro, M., et al. Tumor 72, 135, (1986)
Givan, A.L. Flow Cytometry: First Principles New York , (1992)
Corp MSDS 1 (1), 519:B / FT-IR 1 (2), 816:C / FT-IR 2 (3), 3842:D / FT-NMR 1 (3), 375:A / IR-Spectra (3), 1357:C / IR-Spectra (2), 1182:A / NMR-Reference 2 (2), 695:B / RegBook 1 (2), 2571:C / Sax 6, 525 / Sigma FT-IR 1 (1), 763:B / Structure Index 1, 406:A:7
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|S6269||Sigma lab markers, Extra-Fine tip, blue|
|B8434||Monoclonal Anti-BrdU antibody produced in mouse, ~1.5 mg/mL, clone BU-33, purified immunoglobulin, buffered aqueous solution|
|B2531||Monoclonal Anti-BrdU antibody produced in mouse, clone BU-33, ascites fluid, Immunohistology Grade|
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