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B6556 Sigma

BCMA/Fc Chimera human

>95% (SDS-PAGE), recombinant, expressed in HEK 293 cells, lyophilized powder

Synonym: B cell maturation



Related Categories Cell Biology, Cell Signaling and Neuroscience, Cytokines and Growth Factors, Cytokines, Growth Factors and Hormones, TNF Receptors,
recombinant   expressed in HEK 293 cells
assay   >95% (SDS-PAGE)
form   lyophilized powder
mol wt   mol wt ~40 kDa by SDS-PAGE (reducing)
shipped in   wet ice
storage temp.   −20°C
Gene Information   human ... TNFRSF17(608)


Analysis Note

Inhibits BAFF- and April-mediated B cell activation. May be used to detect cell surface BAFF by flow cytometry.

Biochem/physiol Actions

The extracellular domain (amino acids 2-54) of human BCMA is fused to the Fc portion of human IgG.

BCMA, a member of the TNF receptor superfamily, binds to the TNF ligands, APRIL and BAFF. It stimulates the production of IgM in peripheral blood B cells and increases survival of cultured B cells.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

Price and Availability

All labs need water
Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.


Certificate of Analysis

Protocols & Articles
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