• USA Home
  • B6556 - BCMA/Fc Chimera human

EMAIL THIS PAGE TO A FRIEND
B6556 Sigma

BCMA/Fc Chimera human

>95% (SDS-PAGE), recombinant, expressed in HEK 293 cells, lyophilized powder

Synonym: B cell maturation

Purchase

Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Cytokines and Growth Factors, Cytokines, Growth Factors and Hormones, TNF Receptors,
recombinant   expressed in HEK 293 cells
assay   >95% (SDS-PAGE)
form   lyophilized powder
mol wt   mol wt ~40 kDa by SDS-PAGE (reducing)
shipped in   wet ice
storage temp.   −20°C
Gene Information   human ... TNFRSF17(608)

Description

Analysis Note

Inhibits BAFF- and April-mediated B cell activation. May be used to detect cell surface BAFF by flow cytometry.

Biochem/physiol Actions

The extracellular domain (amino acids 2-54) of human BCMA is fused to the Fc portion of human IgG.

BCMA, a member of the TNF receptor superfamily, binds to the TNF ligands, APRIL and BAFF. It stimulates the production of IgM in peripheral blood B cells and increases survival of cultured B cells.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

Price and Availability


All labs need water
Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.

Documents

Certificate of Analysis

Protocols & Articles
Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?