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B6906 Sigma

Aloin

from Aloe barbadensis Miller leaves, ≥97%

Synonym: 1,8-Dihydroxy-10-(β-D-glucopyranosyl)-3-(hydroxymethyl)-9(10H)-anthracenone, 10-β-D-Glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)-9(10H)-anthracenone, Aloin A, Barbaloin

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Properties

Related Categories Aloe Vera, Biochemicals and Reagents, Carbohydrates, Carbohydrates A to Z, Carbohydrates A-C,
biological source   from Aloe barbadensis Miller leaves
InChI Key   AFHJQYHRLPMKHU-OSYMLPPYSA-N
assay   ≥97%
solubility   methanol: soluble100 mg/mL, clear to very slightly hazy, light yellow to yellow
storage temp.   2-8°C

Description

Packaging

25, 100 mg in poly bottle

Application

Aloin, a natural mixed diastereomer (A/B) anthracycline from aloe plant, may be studied as a chemopreventive factor and antineoplastic agent. Aloin inhibits angiogenesis, enhances melanogenesis and regulates transglutaminase activity. Aloin may be used to assess its activity as a selective phosphodiesterase inhibitor. Aloin A is used as a stabilizer in the preparation of gold and silver nanoparticles.

Biochem/physiol Actions

Purgative activity in rats requires activation by Eubacterium sp. strain BAR or similar intestinal anaerobe, presumably by conversion to aloe-emodin anthrone.

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Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
LZ6520000

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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