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B7405 Sigma

Monoclonal Anti-Digoxin−Biotin antibody produced in mouse

clone DI-22, purified immunoglobulin, buffered aqueous solution

Synonym: Monoclonal Anti-Digoxin

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Properties

Related Categories Alphabetical Index, Antibodies, Antibodies to Digoxin, DE-DL, Molecular Biology,
biological source   mouse
antibody form   purified immunoglobulin
clone   DI-22, monoclonal
form   buffered aqueous solution
application(s)   indirect ELISA: 1:10,000 using digoxin-labeled biomolecule
  western blot: 1:500 using using digoxin-labeled biomolecule
isotype   IgG1
conjugate   biotin conjugate
shipped in   dry ice
storage temp.   −20°C

Description

Immunogen

Digoxin-KLH.

Specificity

Antibody is specific for digoxin and shows a high affinity for digoxigenin.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% BSA and 15 mM sodium azide

Application

Monoclonal Anti-Digoxin-Biotin antibody produced in mouse may be used for ELISA at a dilution of 1:10,000 and for dot blots at a dilution of 1:500. It was also used to stain apoptotic cells in cervical carcinoma sections by TUNEL technique.

Biochem/physiol Actions

Digoxin is a phytoestrogen that binds estrogen receptors and produces inotropic effects in cardiac muscle. Studies show that digoxin decreases the risk of breast and uterus cancers that are estrogen sensitive.

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Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2
Protocols & Articles

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Peer-Reviewed Papers
15

References

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