Budesonide
≥99%
DOWNLOAD MSDS (PDF)Synonym:
16,17-
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CAS Number 51333-22-3
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Empirical Formula (Hill Notation) C25H34O6
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Molecular Weight 430.53
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EC Number 257-139-7
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MDL number MFCD00083259
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PubChem Substance ID 24278277
Properties
| Related Categories | Anti-proliferative Agents, Approved Therapeutics/Drug Candidates, AstraZeneca, B, Bioactive Small Molecules, |
| assay | ≥99% |
| Gene Information |
human ... IFNG(3458), IL5(3567) rat ... Nr3c1(24413) |
Description
Biochem/physiol Actions
Budesonide is a second generation glucocorticoid with low systemic absorption. It is used as an anti-inflammatory agent in the treatment of asthma, rhinitis, and inflammatory bowel disease. It inhibits the expression of chemokine mRNA and production of eotaxin and RANTES protein in primary human bronchial epithelial cells. Budesonide is currently in clinical trials for the prevention of lung cancer. It shows inhibitory effects on benzo[a]pyrene-induced carcinogenesis of the lung in mice.
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