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B9680 Sigma

Bay u9773

≥98% (HPLC), oil

Synonym: 6(R)-(4-Carboxyphenylthio)-5(S)-hydroxy-7(E),9(E),11(E),14(Z)-eicosatetraenoic acid

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Properties

Related Categories Approved Therapeutics/Drug Candidates, Arachidonic Acid Cascade, B, Bayer, Bioactive Small Molecule Alphabetical Index,
InChI Key   PKJINWOACFYDQN-RBVMPENBSA-N
assay   ≥98% (HPLC)
form   oil
color   white
solubility   DMSO: >25 mg/mL
  ethanol: >25 mg/mL
originator   Bayer
shipped in   dry ice
storage temp.   −70°C

Description

Biochem/physiol Actions

Subtype-selective cysteinyl-leukotriene (Cys-Lt) antagonist.

Features and Benefits

This compound is featured on the Leukotriene Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Bayer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

The Role of Inflammation in Neurodegeneration

It is well established that the brain can sense and react to peripheral insults through the rapid induction of fever and other neuroendocrine changes in response to events such as infection and tissu...
Scott Hauser, Technology Transfer Specialist, Sigma® Life Science
Biofiles, Vol. 8, No. 19
Keywords: Adhesion, Central Nervous System, Diseases, Gene expression, Inflammation, Neurodegenerative Diseases, Reductions

Peer-Reviewed Papers
15

References

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