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C0297 Sigma

Monoclonal Anti-Caldesmon antibody produced in mouse

clone C21, ascites fluid

Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Intracellular Calcium Signaling, Antibodies to Actin-associated Proteins/Myosin,
species reactivity   mammals
application(s)   indirect ELISA: 1:2,500
  western blot: suitable
clone   C21, monoclonal
antibody form   ascites fluid
isotype   IgG1
contains   15 mM sodium azide
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... CALD1(800)
mouse ... Cald1(109624)
rat ... Cald1(25687)
biological source   mouse
conjugate   unconjugated

Description

Immunogen

chicken caldesmon

Specificity

The antibody is directed against an epitope near the carboxy-terminus, Ca2+/calmodulin and F-actin binding site of caldesmon. Using ELISA, the antibody is able to inhibit caldesmon binding to Ca2+/calmodulin and F-actin. By immunoblotting, the antibody shows broad species reactivity to non-muscle caldesmon of mammalian cells.

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