C0378 Sigma

Chloramphenicol

≥98% (TLC)

DOWNLOAD MSDS (PDF)

Synonym: D-(−)-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-β-(4-nitrophenyl)ethyl]acetamide, D-(−)-threo-2-Dichloroacetamido-1-(4-nitrophenyl)-1,3-propanediol, D-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-4-nitrophenethyl]acetamide, Chloromycetin

Description

Application

Used as a seletion agent for transformed cells containing chloramphenicol resistance genes.

Biochem/physiol Actions

Mode of Action: Inhibits translation on the 50S ribosomal subunit at the peptidyltransferase step (elongation inhibition). Bacteriostatic.
Mode of Resistance: Acetylation by chloramphenicol acetyltransferase (cat gene).

Packaging

1 kg in poly bottle

5, 25, 100, 500 g in poly bottle

Protocols & Applications

Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information

Price and Availability

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