• USA Home
  • C0412 - Concanavalin A from Canavalia ensiformis (Jack bean)

EMAIL THIS PAGE TO A FRIEND
C0412 Sigma

Concanavalin A from Canavalia ensiformis (Jack bean)

Type IV-S, lyophilized powder, γ-irradiated, BioReagent, suitable for cell culture

Synonym: Con A

Purchase

Properties

Related Categories Cell Biology, Cell Culture, Cell Signaling and Neuroscience, Concanavalin A (Con A), Glycan Recognizing Proteins,
sterility   γ-irradiated
type   Type IV-S
product line   BioReagent
form   lyophilized powder
impurities   salt, essentially free
solubility   PBS: soluble5 mg/mL, slightly hazy
  H2O: soluble, slightly hazy
suitability   suitable for cell culture
storage temp.   −20°C

Description

Analysis Note

Where reported, agglutination activity is expressed in μg/ml and is determined from serial dilutions in phosphate buffered saline, pH 6.8, containing Ca2+ and Mn2+ of a 1 mg per mL solution. This activity is the lowest concentration to agglutinate a 2% suspension of human erythrocytes after 1 hr incubation at 25 °C.

Biochem/physiol Actions

Con A is not blood group specific but has an affinity for terminal α-D-mannosyl and α-D-glucosyl residues. Ca2+ and Mn2+ ions are required for activity. Con A dissociates into dimers at pH 5.6 or below. Between pH 5.8 and pH 7.0, Con A exists as a tetramer; above pH 7.0 higher aggregates are formed. Con A exhibits mitogenic activity which is dependent on its degree of aggregation. Succinylation results in an active dimeric form which remains a dimer above pH 5.6.

Price and Availability


Amplified Detection

Amicon Pro Purification System

Filter out uncertainty.
Safety & Documentation

Safety Information

Symbol 
GHS08  GHS08
Signal word 
Danger
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
GK6890000

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Related Products

related product

Product #

Description

Add to Cart

92210 Timestrip Plus 0 °C
06693 Timestrip Plus -20 °C

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?