Cambinol
≥97% (HPLC), white powder
DOWNLOAD MSDS (PDF)Synonym:
5-
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CAS Number 14513-15-6
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Empirical Formula (Hill Notation) C21H16N2O2S
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Molecular Weight 360.43
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MDL number MFCD09057543
Properties
| Related Categories | Bioactive Small Molecules, Bioactive Small Molecules for Epigenetic Research, C-CH, Cell Biology, Cell Signaling and Neuroscience, |
| assay | ≥97% (HPLC) |
| form | white powder |
| solubility | DMSO: ≥10 mg/mL |
| storage temp. | room temp |
Description
Biochem/physiol Actions
Cambinol is a Sirtuin (Human Silent Information Regulator) Type 1/2 Inhibitor. Sirtuins are structurally and mechanistically unrelated to HDACs Class 1 & 2 deacetylases but share many protein targets. HDAC is a large complex enzyme family involved in epigenetic-control of gene expression. Sirt2 has an IC50 equal to 59 μM.
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