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C0567 Sigma

(−)-Catechin

≥97% (HPLC), from green tea

Synonym: (−)-trans-3,3′,4′,5,7-Pentahydroxyflavane, (2S,3R)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol

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DISCOVER Bioactive Small Molecules

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(+)-Catechin hydrate

≥96.0% (sum of enantiomers, HPLC)

(−)-Catechin gallate

≥98% (HPLC), from green tea

(−)-Epicatechin

≥98% (HPLC), from green tea

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Safety Information

WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Discover Bioactive Small Molecules for Nitric Oxide Cell & Stress Research

Exposure to harsh conditions, cellular damage, and other factors can cause stress on cells. Stress attributed directly and indirectly to oxygen is referred to as oxidative stress, which is imposed on...
Keywords: Antimicrobials, Bioactive small molecules, Cancer, Diseases, Neurodegenerative Diseases, Oxidations

Peer-Reviewed Papers

References

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Inhibition of Plasmodium falciparum fatty acid biosynthesis: evaluation of FabG, FabZ, and FabI as drug targets for flavonoids. Deniz Tasdemir et al J. Med. Chem. 49, 3345-53, (2006)

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An efficient and economical MTT assay for determining the antioxidant activity of plant natural product extracts and pure compounds. Yunbao Liu et al J. Nat. Prod. 73, 1193-5, (2010)

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Flavonoids as opioid receptor ligands: identification and preliminary structure-activity relationships. Peter L Katavic et al J. Nat. Prod. 70, 1278-82, (2007)

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Potent inhibitor scaffold against Trypanosoma cruzi trans-sialidase. Shingo Arioka et al Bioorg. Med. Chem. 18, 1633-40, (2010)

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Tea catechins inhibit hepatocyte growth factor receptor (MET kinase) activity in human colon cancer cells: kinetic and molecular docking studies. Christine A Larsen et al J. Med. Chem. 52, 6543-5, (2009)

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Sulfonamide chalcone as a new class of alpha-glucosidase inhibitors. Woo Duck Seo et al Bioorg. Med. Chem. Lett. 15, 5514-6, (2005)

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Galactolipids from Bauhinia racemosa as a new class of antifilarial agents against human lymphatic filarial parasite, Brugia malayi. Koneni V Sashidhara et al Eur. J. Med. Chem. 50, 230-5, (2012)

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Catechin gallates are NADP+-competitive inhibitors of glucose-6-phosphate dehydrogenase and other enzymes that employ NADP+ as a coenzyme. Eui Seok Shin et al Bioorg. Med. Chem. 16, 3580-6, (2008)

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Merck 14,1902

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