|Related Categories||ALDH1A, Apoptosis Reagents, Apoptosis and Cell Cycle, Bioactive Small Molecules, Breast Cancer Stem Cell Markers,|
|Gene Information||human ... ALDH1A1(216), ALDH1B1(219)|
1, 5, 10, 25 g in glass bottle
Cyclophosphamide is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity.
Certificate of Analysis
Certificate of Origin
|Precautionary statements||P201-P301 + P310-P308 + P313|
|Personal Protective Equipment||Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges|
|Hazard Codes (Europe)||T|
|Risk Statements (Europe)||45-25|
|Safety Statements (Europe)||53-45|
|RIDADR||UN 3464 6.1/PG 3|
|Flash Point(F)||235.4 °F|
|Flash Point(C)||113 °C|
Chemotherapy is the treatment of choice against many types of cancer. However, over time chemotherapeutic drugs can become less effective due to the development of resistance that involves a group of...
BioFiles 2007, 2.4, 7.
Keywords: Absorption, Cancer, Clinical, Cloning, Combinatorial synthesis, Diseases, Enzymology, Gene expression, Genetic, Immunology, Pharmaceutical, Reductions, Transfection
Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete. The expansion of the carcinogenesi...
BioFiles 2008, 3.5, 18.
Keywords: Acetylations, Adhesion, Alkylations, Apoptosis, Cancer, Carcinogens, Cell division, Cell proliferation, Cell signaling, DNA microarrays, Drug discovery, Environmental, Epigenetics, Gene expression, Genetic, Hormones, Metabolism, Methylations, Microarray Analysis, Mutagens, PAGE, Recombination, Reductions, Transcription, transformation
Mechanisms by which chemotherapeutic agents augment the antitumor effects of tumor necrosis factor: involvement of the pattern shift of cytokines from Th2 to Th1 in tumor lesions. Inagawa, H., et al. Anticancer Res. 18, 3957-3964, (1998)
Aldrich MSDS 1, 537:C / Corp MSDS 1 (1), 992:C / FT-IR 1 (1), 920:C / FT-IR 2 (1), 1582:D / FT-NMR 1 (1), 1500:B / IR-Spectra (3), 552:G / NMR-Reference 2 (2), 872:B / RegBook 1 (1), 1119:E / Sax 6, 1277 / Sigma FT-IR 1 (2), 418:D / Structure Index 1, 173:D:4
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