|Related Categories||ALDH1A, Apoptosis Reagents, Apoptosis and Cell Cycle, Bioactive Small Molecules, Breast Cancer Stem Cell Markers,|
|Gene Information||human ... ALDH1A1(216), ALDH1B1(219)|
1, 5, 10, 25 g in glass bottle
Cyclophosphamide is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity.
Certificate of Analysis
Certificate of Origin
|Precautionary statements||P201-P301 + P310-P308 + P313|
|Personal Protective Equipment||Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges|
|Hazard Codes (Europe)||T|
|Risk Statements (Europe)||45-25|
|Safety Statements (Europe)||53-45|
|RIDADR||UN 3464 6.1 / PGIII|
|Flash Point(F)||235.4 °F|
|Flash Point(C)||113 °C|
Chemotherapy is the treatment of choice against many types of cancer. However, over time chemotherapeutic drugs can become less effective due to the development of resistance that involves a group of...
BioFiles 2007, 2.4, 7.
Keywords: Absorption, Cancer, Clinical, Cloning, Combinatorial synthesis, Diseases, Enzymology, Gene expression, Genetic, Immunology, Pharmaceutical, Reductions, Transfection
Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete. The expansion of the carcinogenesi...
BioFiles 2008, 3.5, 18.
Keywords: Acetylations, Adhesion, Alkylations, Apoptosis, Cancer, Carcinogens, Cell division, Cell proliferation, Cell signaling, DNA microarrays, Drug discovery, Environmental, Epigenetics, Gene expression, Genetic, Hormones, Metabolism, Methylations, Microarray Analysis, Mutagens, PAGE, Recombination, Reductions, Transcription, transformation
[A case of triple-negative breast cancer achieved pCR by epirubicin and cyclophosphamide(EC)therapy followed by gemcitabine plus paclitaxel combination preoperative therapy]. Saito M, Fujita S, Sakuma T, et al. Gan To Kagaku Ryoho. 40(5), 623-5, (2013)
[Study on inhibitory effect of combined administration of bear bile powder and cyclophosphamide on colorectal cancer liver metastasis by regulating tumor microenvironment]. Cui W, Liu S, Yang M, et al. Zhongguo Zhong Yao Za Zhi 38(7), 1036-40, (2013)
[Effectiveness and toxicity of MOPP, ABVD, BEACOPP chemotherapy in first-diagnosed Hodgkin lymphoma with a poor prognosis]. Filatova LV, Plotnikova AA, Gershanovich ML, et al. Vopr. Onkol. 59(2), 59-65, (2013)
Secretory clusterin (sCLU) overexpression is associated with resistance to preoperative neoadjuvant chemotherapy in primary breast cancer. Niu ZH, Wang Y, Chun B, et al. Eur. Rev. Med. Pharmacol. Sci. 17(10), 1337-44, (2013)
Compound K is able to ameliorate the impaired cognitive function and hippocampal neurogenesis following chemotherapy treatment. Hou JG, Xue JJ, Lee MR, et al. Biochem. Biophys. Res. Commun. 436(1), 104-9, (2013)
[Development of syndrome of inappropriate secretion of ADH and reversible posterior leukoencephalopathy during initial rituximab-CHOP therapy in a patient with diffuse large B-cell lymphoma]. Mizutani M, Nakamori Y, Sakaguchi H, et al. Rinsho. Ketsueki. 54(3), 269-72, (2013)
Progressive multifocal encephalopathy after cyclophosphamide in granulomatosis with polyangiitis (Wegener) patients: case report and review of literature. Pugnet G, Pagnoux C, Bézanahary H, et al. Clin. Exp. Rheumatol. 31(1 Suppl 75), S62-4, (2013)
Unusual case of recurrent extraneural metastatic medulloblastoma in a young adult: durable complete remission with Ewing sarcoma chemotherapy regimen and consolidation with autologous bone marrow transplantation and local radiation. Clement J, Varlotto J, Rybka W, et al. J. Clin. Oncol. 31(19), e316-9, (2013)
Alterations in deoxyribonucleic acid (DNA) methylation patterns of Calca, Timp3, Mmp2, and Igf2r are associated with chronic cystitis in a cyclophosphamide-induced mouse model. Choi IS, Yu K, Kim J, et al. Urology 82(1), 253.e9-15, (2013)
Dose-intense etoposide-cyclophosphamide without stem cell transplantation for patients with intermediate and high cytogenetic risk primary refractory and relapsed acute myeloid leukemia. Trifilio S, Zhou Z, Altman J, et al. Leuk. Res. 37(8), 872-6, (2013)
Mechanisms by which chemotherapeutic agents augment the antitumor effects of tumor necrosis factor: involvement of the pattern shift of cytokines from Th2 to Th1 in tumor lesions. Inagawa, H., et al. Anticancer Res. 18, 3957-3964, (1998)
Aldrich MSDS 1, 537:C / Corp MSDS 1 (1), 992:C / FT-IR 1 (1), 920:C / FT-IR 2 (1), 1582:D / FT-NMR 1 (1), 1500:B / IR-Spectra (3), 552:G / NMR-Reference 2 (2), 872:B / RegBook 1 (1), 1119:E / Sax 6, 1277 / Sigma FT-IR 1 (2), 418:D / Structure Index 1, 173:D:4
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Need larger quantities for your development, manufacturing or research applications?