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C0780 Sigma

Creatine

anhydrous

Synonym: (α-Methylguanido)acetic acid, N-Amidinosarcosine

  • CAS Number 57-00-1

  • Linear Formula H2NC(=NH)N(CH3)CH2CO2H

  • Molecular Weight 131.13

  •  Beilstein Registry Number 907175

  •  EC Number 200-306-6

  •  MDL number MFCD00004282

  •  PubChem Substance ID 24892273

  • Popular Documents:  FTNMR (PDF)  

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Description

Packaging

10 mg in autosample vial

50, 100, 500 g in poly bottle

Application

Creatine (Cr) and phosphocreatine (PCr) are involved with rapid ATP production primarily in skeletal muscle tissue via the action of creatine kinase(s). Creatine may be used as a supplement to study its uptake mechanism and metabolism of action.

Biochem/physiol Actions

Creatine is a nitrogenous compound that acts as a high-energy reservoir for the rapid regeneration of ATP. Approximately 95% of creatine is found in skeletal muscle, primarily as phosphocreatine. Creatine can be acquired through dietary consumption or formed from L-arginine, glycine, and L-methionine in a multi-step reaction that occurs in the kidneys and liver. Creatine is then transported to muscle tissue. Creatine supplementation is used for the enhancement of sports performance, primarily by increasing muscle mass. Creatine is also being investigated as a treatment of neuromuscular diseases, where it may aid in neuroprotection and by improving the cellular bioenergetic state.

Price and Availability


Laboratory Gloves

All labs need water
Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles

Articles

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

Peer-Reviewed Papers
15

References

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