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C0791 Sigma

Monoclonal Anti-Cytokeratin Peptide 13 antibody produced in mouse

clone KS-1A3, ascites fluid

Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies to Cell and Organelle Proteins, Antibodies to Cytokeratins,
species reactivity   human
application(s)   immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
  indirect immunofluorescence: 1:100 using formalin-fixed, paraffin-embedded human tissue sections.1
  microarray: suitable
clone   KS-1A3, monoclonal
antibody form   ascites fluid
isotype   IgG1
contains   15 mM sodium azide
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... KRT13(3860)
biological source   mouse
conjugate   unconjugated

Description

Immunogen

cultured human epidermoid carcinoma cell line A-431.

Specificity

The antibody reacts with squamous, non-keratinized epithelium, transitional epithelium, pseudostratified epithelium, and myoepithelium.

Application

Monoclonal Anti-Cytokeratin Peptide 13 antibody produced in mouse is suitable for the following applications:
• Immunohistochemistry (formalin-fixed, paraffin-embedded sections)
• Indirect immunofluorescence at a working dilution of 1:100 using formalin-fixed, paraffin-embedded human tissue sections.
• Microarray

Biochem/physiol Actions

Cytokeratins are proteins of keratin-containing intermediate filaments that provide mechanical support and other additional functions in epithelial cells. It is found in the intracytoplasmic cytoskeleton of epithelial tissue. Epithelial tissue expresses cytokeratin subunits in a specific and stable pattern. Cytokeratins along with vimentin are involved in cell proliferation, migration and differentiation of preodontoblasts and preameloblasts. The intermediate-sized filaments are abundant in human endothelial cells and are mostly of vimentin type.

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