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C0875 Sigma

Calcein

Used for the fluorometric determination of calcium and EDTA titration of calcium in the presence of magnesium.

Synonym: Bis[N,N−bis(carboxymethyl)aminomethyl]fluorescein, Fluorescein-bis(methyliminodiacetic acid), Fluorexon

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Packaging

5, 10, 25 g in glass bottle

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TruPAGE™ Pre-cast Polyacrylamide Gels


TruPAGE™ Pre-cast Polyacrylamide GelsTruPAGE Gels run true every time!

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Calcein AM solution

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Safety & Documentation

Safety Information

WGK Germany 
3

Protocols & Articles

Articles

ABC Transporters and Cancer Drug Resistance

Chemotherapy is the treatment of choice against many types of cancer. However, over time chemotherapeutic drugs can become less effective due to the development of resistance that involves a group of...
BioFiles 2007, 2.4, 7.
Keywords: Absorption, Cancer, Clinical, Cloning, Combinatorial synthesis, Diseases, Enzymology, Gene expression, Genetic, Immunology, Pharmaceutical, Reductions, Search, Transfection, Vectors

Sensor Dyes

In 1998 R.F. Furchgott, L.J. Ignarro, and F. Murad received the Nobel Prize in Physiology and Medicine for their discoveries concerning nitric oxide as a signaling molecule in the cardiovascular syst...
Monika Baeumle
BioFiles 2011, 6.3, 23.
Keywords: Applications, Biochemistry, Biological processes, Cancer, Cardiovascular, Central Nervous System, Diseases, Extinction coefficient, Indicators, Inflammation, Methods, Microscopy, Neurotransmission, Sol-gel, Type

Peer-Reviewed Papers

References

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Bone Density, Strength, And Formation In Adult Cathepsin K (-/-) Mice. Pennypacker, B., et al. Bone 44, 199-207, (2009)

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The elongation rate of RNA polymerase II in zebrafish and its significance in the somite segmentation clock. Hanisch A, Holder MV, Choorapoikayil S, et al. Development 140(2), 444-53, (2013)

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Rapid bactericidal action of alpha-mangostin against MRSA as an outcome of membrane targeting. Koh JJ, Qiu S, Zou H, et al. Biochim. Biophys. Acta 1828(2), 834-44, (2013)

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Kindlin-3-mediated signaling from multiple integrin classes is required for osteoclast-mediated bone resorption. Schmidt S J. Cell Biol. 192(5), 883-97, (2011)

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Single vesicle analysis reveals nanoscale membrane curvature selective pore formation in lipid membranes by an antiviral α-helical peptide. Tabaei SR, Rabe M, Zhdanov VP, et al. Nano Lett. 12(11), 5719-25, (2012)

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Effects of surfactin on membrane models displaying lipid phase separation. Deleu M, Lorent J, Lins L, et al. Biochim. Biophys. Acta 1828(2), 801-15, (2013)

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In vitro antitumor activity of methotrexate via pH-sensitive chitosan nanoparticles. Nogueira DR, Tavano L, Mitjans M, et al. Biomaterials 34(11), 2758-72, (2013)

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Statistical fluctuation in zeta potential distribution of nanoliposomes measured by on-chip microcapillary electrophoresis. Kato K, Koido M, Kobayashi M, et al. Electrophoresis 34(8), 1212-8, (2013)

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A novel chimeric cell-penetrating peptide with membrane-disruptive properties for efficient endosomal escape. Salomone F, Cardarelli F, Di Luca M, et al. J. Control. Release 163(3), 293-303, (2012)

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A versatile drug delivery system using streptavidin-tagged pegylated liposomes and biotinylated biomaterials. Chen MH, Soda Y, Izawa K, et al. Int. J. Pharm. 454(1), 478-85, (2013)

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Mechanically-induced osteogenesis in the cortical bone of pre- to peripubertal stage and peri- to postpubertal stage mice. Plochocki JH J. Orthop. Surg. Res. 4, 22, (2009)

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Membrane fusion mediated by phospholipase C under endosomal pH conditions. Shimanouchi T, Kawasaki H, Fuse M, et al. Colloids Surf. B Biointerfaces 103, 75-83, (2013)

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Spatiotemporally controlled single cell sonoporation. Fan Z, Liu H, Mayer M, et al. Proc. Natl. Acad. Sci. U. S. A. 109(41), 16486-91, (2012)

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Ultrasonic gene and drug delivery using eLiposomes. Javadi M, Pitt WG, Tracy CM, et al. J. Control. Release 167(1), 92-100, (2013)

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Chemoselective nanoporous membranes via chemically directed assembly of nanoparticles and dendrimers. Park MH, Subramani C, Rana S, et al. Adv. Mater. 24(43), 5862-6, (2012)

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The effect of d-amino acid substitution on the selectivity of temporin L towards target cells: identification of a potent anti-Candida peptide. Grieco P, Carotenuto A, Auriemma L, et al. Biochim. Biophys. Acta 1828(2), 652-60, (2013)

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Integrity and stability of oral liposomes containing bile salts studied in simulated and ex vivo gastrointestinal media. Hu S, Niu M, Hu F, et al. Int. J. Pharm. 441(1-2), 693-700, (2013)

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Ultrasound-induced calcein release from eLiposomes. Lattin JR, Pitt WG, Belnap DM, et al. Ultrasound Med. Biol. 38(12), 2163-73, (2012)

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Treatment of influenza virus with beta-propiolactone alters viral membrane fusion. Bonnafous P, Nicolaï MC, Taveau JC, et al. Biochim. Biophys. Acta 1838(1 Pt B), 355-63, (2014)

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Carboxyl-terminated PAMAM dendrimer interaction with 1-palmitoyl-2-oleoyl phosphocholine bilayers. Evans KO, Laszlo JA, and Compton DL Biochim. Biophys. Acta 1838(1 Pt B), 445-55, (2014)

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aP2-Cre-mediated inactivation of acetyl-CoA carboxylase 1 causes growth retardation and reduced lipid accumulation in adipose tissues. Mao J Proc. Natl. Acad. Sci. U. S. A. 106(41), 17576-81, (2009)

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Determination of hyperin in seed of Cuscuta chinensis Lam. by enhanced chemiluminescence of CdTe quantum dots on calcein/K3Fe(CN)6 system. Kang J, Li X, Geng J, et al. Food Chem. 134(4), 2383-8, (2012)

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Importance of polarity of the α4-α5 loop residue-Asn(166) in the pore-forming domain of the Bacillus thuringiensis Cry4Ba toxin: implications for ion permeation and pore opening. Juntadech T, Kanintronkul Y, Kanchanawarin C, et al. Biochim. Biophys. Acta 1838(1 Pt B), 319-27, (2014)

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Initial stages of calcium uptake and mineral deposition in sea urchin embryos. Vidavsky N, Addadi S, Mahamid J, et al. Proc. Natl. Acad. Sci. U. S. A. 111(1), 39-44, (2014)

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Aurein 2.3 functionality is supported by oblique orientated α-helical formation. Mura M, Dennison SR, Zvelindovsky AV, et al. Biochim. Biophys. Acta 1828(2), 586-94, (2013)

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Joint loading-driven bone formation and signaling pathways predicted from genome-wide expression profiles. Ping Zhang et al Bone 44, 989-98, (2009)

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An ultrasensitive and selective fluorescence assay for Sudan I and III against the influence of Sudan II and IV. Huang ST, Yang LF, Li NB, et al. Biosens. Bioelectron. 42, 136-40, (2013)

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Blockade of receptor-activated G(i) signaling in osteoblasts in vivo leads to site-specific increases in cortical and cancellous bone formation. Millard SM, Louie AM, Wattanachanya L, et al. J. Bone Miner Res. 26(4), 822-32, (2011)

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Antifungal effect and pore-forming action of lactoferricin B like peptide derived from centipede Scolopendra subspinipes mutilans. Choi H, Hwang JS, and Lee DG Biochim. Biophys. Acta 1828(11), 2745-50, (2013)

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A biophysical approach to menadione membrane interactions: relevance for menadione-induced mitochondria dysfunction and related deleterious/therapeutic effects. Monteiro JP, Martins AF, Nunes C, et al. Biochim. Biophys. Acta 1828(8), 1899-908, (2013)

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src family kinases regulate renal epithelial paracellular permeability barrier through an occludin-independent mechanism. Caswell D, Jaggi S, Axis J, et al. J. Cell Physiol. 228(6), 1210-20, (2013)

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Restricted neural plasticity in vestibulospinal pathways after unilateral labyrinthectomy as the origin for scoliotic deformations. Lambert FM, Malinvaud D, Gratacap M, et al. J. Neurosci. 33(16), 6845-56, (2013)

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Delayed pubertal development by hypothalamic suppression causes an increase in periosteal modeling but a reduction in bone strength in growing female rats. Yingling VR Bone 42(6), 1137-43, (2008)

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Tunicamycin depresses p-glycoprotein glycosylation without an effect on its membrane localization and drug efflux activity in l1210 cells. Sereš M, Cholujová D, Bubenčíkova T, et al. Int. J. Mol. Sci. 12(11), 7772-84, (2011)

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Induced ablation of Bmp1 and Tll1 produces osteogenesis imperfecta in mice. Muir AM, Ren Y, Butz DH, et al. Hum. Mol. Genet. 23(12), 3085-101, (2014)

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Isolation of (-)-olivil-9'-O-β-d-glucopyranoside from Sambucus williamsii and its antifungal effects with membrane-disruptive action. Choi H, Lee J, Chang YS, et al. Biochim. Biophys. Acta 1828(8), 2002-6, (2013)

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Involvement of ABCB1 and ABCC1 transporters in sea urchin Echinometra lucunter fertilization. Silva-Neta HL, Torrezan E, de Araújo Leite JC, et al. Mol. Reprod. Dev. 79(12), 861-9, (2012)

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Deficiency of osteoblastic Arl6ip5 impaired osteoblast differentiation and enhanced osteoclastogenesis via disturbance of ER calcium homeostasis and induction of ER stress-mediated apoptosis. Wu Y, Yang M, Fan J, et al. Cell Death Dis. 5, e1464, (2014)

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Antifungal property of hibicuslide C and its membrane-active mechanism in Candida albicans. Hwang JH, Jin Q, Woo ER, et al. Biochimie 95(10), 1917-22, (2013)

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Towards an understanding of the release behavior of temperature-sensitive liposomes: a possible explanation of the "pseudoequilibrium" release behavior at the phase transition temperature. Zhang X, Luckham PF, Hughes AD, et al. J. Liposome Res. 23(3), 167-73, (2013)

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Effects of rhinacanthin-C on function and expression of drug efflux transporters in Caco-2 cells. Wongwanakul R, Vardhanabhuti N, Siripong P, et al. Fitoterapia 89, 80-5, (2013)

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Development of a novel primer combination to detect pathogenic Leptospira by loop-mediated isothermal amplification. Suwancharoen D, Kulchim C, Chirathaworn C, et al. J. Microbiol. Methods 91(1), 171-3, (2012)

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Reversible and irreversible electroporation of cell suspensions flowing through a localized DC electric field. Korohoda W, Grys M, and Madeja Z Cell Mol. Biol. Lett. 18(1), 102-19, (2013)

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Preparation and characterization of stable pH-sensitive vesicles composed of α-tocopherol hemisuccinate. Xu H, Deng YH, Wang KQ, et al. AAPS PharmSciTech 13(4), 1377-85, (2012)

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Biomembrane damage caused by exposure to multi-walled carbon nanotubes. Shimizu K, Uchiyama A, Yamashita M, et al. J. Toxicol. Sci. 38(1), 7-12, (2013)

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The antifungal activity and membrane-disruptive action of dioscin extracted from Dioscorea nipponica. Cho J, Choi H, Lee J, Kim MS, et al. Biochim. Biophys. Acta 1828, 1153-1158, (2012)

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