• USA Home
  • C1108 - Anti-Cannabinoid Receptor 1 antibody produced in rabbit

EMAIL THIS PAGE TO A FRIEND
C1108 Sigma

Anti-Cannabinoid Receptor 1 antibody produced in rabbit

affinity isolated antibody, buffered aqueous glycerol solution

Purchase

Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Neurotransmission, Antibodies to Neurotransmitter Receptors, CAM-CB,
species reactivity   rat, human
application(s)   immunocytochemistry: suitable
  western blot: suitable
clone   polyclonal
concentration   1 mg/mL
antibody form   affinity isolated antibody
form   buffered aqueous glycerol solution
mol wt   antigen mol wt ~52 kDa
shipped in   wet ice
storage temp.   −20°C
Gene Information   human ... CNR1(1268)
rat ... Cnr1(25248)
biological source   rabbit
conjugate   unconjugated

Description

Immunogen

fusion protein containing amino acids 1-99 of the human CB1 receptor.

Physical form

Solution in phosphate buffered saline containing 1 mg/ml bovine serum albumin, 50% glycerol, and 0.05% sodium azide.

Application

Anti-Cannabinoid Receptor 1 antibody produced in rabbit is suitable for western blotting at a working dilution of 1:250 and for immunocytochemistry at a working dilution of 1:1000.

Biochem/physiol Actions

Cannabinoids exert their well-known physiological effects through two G-protein coupled receptors, CB1 and CB2. The cannabinoid receptor type 1 (CB1) is widely distributed in mammalian tissues, with the highest concentrations found in brain neurons while CB2 receptor function primarily in the peripheral immune system, found in spleen and may be present in the central nervous system, including the retina. The cannabinoid receptor type 1 are involved in modulation of adenylate cyclase and ion channels. It is also involved in the modulation of nociception, movement, learning and memory, emotion and many other neuronal processes. It also plays an essential role in drug addiction. CB1 receptor blockade may be useful for treatment of angiotensin II-dependent hypertension and associated metabolic syndrome.

Price and Availability


Antibody Explorer

Explore with Confidence
Safety & Documentation

Safety Information

RIDADR  NONH for all modes of transport
WGK Germany  3
Protocols & Articles

Related Content

Antibody Explorer | Buy Primary & Secondary Antibodies

Monoclonal and polyclonal primary antibodies are focused on cell biology, neurobiology and molecular biology. Secondary antibodies targeting multiple host’s IgG are conjugated to alkaline phosphatase...
Keywords: Amplification, Buffers, Cell biology, Enzyme-linked immunosorbent assay, Immunofluorescence, Immunohistochemistry, Inflammation, Molecular biology, Phosphorylations, Purification, Western blot

Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?