C1129 Sigma

Cholic acid

from ox or sheep bile, ≥98%

Synonym: 3α,7α,12α-Trihydroxy-5β-cholanic acid, Cholanic acid



Non-denaturing ionic detergent used for extraction of membrane proteins.

Dietary cholic acid has been used in a study to assess its effect on colonic epithelial cell proliferation. 1 It has also been used in a study to investigate extractions and comparisons of human erythrocyte ghosts. 2

Biochem/physiol Actions

Bile Acid

General description

Cholic acid is a major primary bile acid produced in the liver which facilitates fat absorption and cholesterol excretion. It is a non-denaturing ionic detergent.


1 kg in poly bottle

25, 100, 500 g in poly bottle

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. C1129.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit

Price and Availability

Suggested Laboratory Gloves

Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.

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